VITAMIN D
Vitamin D, it is also known as vitamin D2( C28H44O) ergocalciferol (calciferol), Vitamin D3(C27H44O) (cholecalciferol).
Vitamin D is a fat-soluble vitamin. It is known as Prehormone as it is the precursor of several metabolites.
HIGH-RISK POPULATION
The impact of vitamin D deficiency has been studied more than 300 years ago as a metabolic disorder Rickets. However, its relationship with vitamin D deficiency has been established only recently Vitamin D deficiency may be due to limited exposure to sunlight, dark skin, dietary deficiency, poor absorption of Vitamin D, gastrointestinal disease, and abnormality of Vitamin D metabolism,
The breastfeeding infants may also develop a deficiency of Vitamin D in absence of dietary supplements. The serum vitamin D is an indicator of deficiency of vitamin D in the body.
People having milk allergy or lactose intolerance are prone to Vitamin D deficiency.
SYNTHESIS
Vitamin D is synthesized from cholesterol. it is synthesized naturally into the body.D2 is found in plants. D3 Cholecalciferol is animal Vitamin D. It is generated from 7 dihydroxy cholesterol in the skin during exposure to ultraviolet light. This precursor is then converted into active 25- hydroxyvitamin D is known as calcidiol in the liver. It is transported to the kidney where it is converted into calcitriol that is 1,25- Tri-hydroxy Vitamin D.
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| SYNTHESIS OF VITAMIN D, UNDER THE EXPOSURE TO SUNLIGHT |
Sources of Vitamin D
A large number of food items are a good source of vitamin D. Cod- liver, egg yolk, cheese has a good amount of D3.
Mushrooms have D2 and if it is exposed to ultraviolet rays it will have increased availability of Vitamin D.
An animal-based dietary item such as beef or chicken has 2-18 times higher vitamin D.
The fortified milk also has an increased amount of Vitamin D.
The uncovered skin’s exposure to ultraviolet rays can produce vitamin D naturally. However, sunscreens, clothing, and dark skin reduce the production of vitamin D.
The sun exposure of skin for 5 to 30 minutes increases the Production of Vitamin D.
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| WHAT IMPROVE VITAMIN D |
Deficiency diseases
Children having vitamin D deficiency develop Rickets.
In adults and adolescence, vitamin D deficiency leads to osteomalacia, in which bones are incompletely or ineffectively mineralized, resulting in weak bones that result in pain. Vitamin D deficiency also results in hypocalcemia and dental abnormalities
The breastfeeding infants develop vitamin D deficiency as human milk does not have a sufficient quantity of Vitamin D. Furthermore it is related to the mother’s level of Vitamin D.
UV exposure is required for such infants to meet their daily requirement of Vitamin D.
· OLDER individuals are least exposed to UV rays so they may develop vitamin D deficiency. The dark skin people also have a high risk of Vitamin D deficiency.
Why do we need Vitamin D
· Vitamin D is required for normal calcium and phosphorous absorption in the body is required for the good health of our bones and muscles.
Vitamin D also found its role in metabolism as it is required by beta cells of the pancreas to secrete insulin thus individuals may develop diabetes 2.
· Vitamin D also regulates blood pressure thus it is linked to cardiovascular diseases.
· People having enough serum vitamin D have a lower risk of cardiovascular diseases.
· Vitamin D is involved in various brain processes.
· Vitamin D receptors are present in neurons and it is known that they are associated with the pathophysiology of depression.
· For healthy life get your daily dose of sunlight.
· Get enough dairy products.
· Animal food supplements give you a dietary option for vitamin D
Well explained
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